BDBM50206160 CHEMBL245621::Halopemide::Halopemide, 8::N-(2-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-fluorobenzamide::N-(2-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-fluorobenzamide::cid_65490

SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O

InChI Key InChIKey=NBHPRWLFLUBAIE-UHFFFAOYSA-N

Data  13 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50206160   

TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  280nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  310nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair